Reginald Owen
Skipper of the Congo Queen
Frank Morgan
The Doctor
Oscar Polk
Umeela
Walter Pidgeon
Mr. Harry Witzel
Clyde Cook
Ted, First Mate of the Congo Queen
Henry O'Neill
The Reverend Dr. Roberts
Jim Davis
Seaplane Pilot (uncredited)
Richard Carlson
Mr. Langford
Hedy Lamarr
Tondelayo
Richard Ainley
Mr. Worthing
Darby Jones
Darby
Martin Wilkins
Native Prisoner (uncredited)
Leigh Whipper
Jim Fish
Delos Jewkes
Native Singer (uncredited)
Bramwell Fletcher
Wilbur Ashley