David Cross
Cain
Vinnie Jones
Sargon
Harold Ramis
Adam
Xander Berkeley
King
Hank Azaria
Abraham
Gia Carides
Queen
Oliver Platt
High Priest
Bill Hader
Shaman
Paul Rudd
Abel (uncredited)
Kyle Gass
Zaftig the Eunuch
Jamal Sims
Dancer
Juno Temple
Eema
Michael Cera
Oh
Rhoda Griffis
Eve
Horatio Sanz
Enmebaragesi
Christopher Mintz-Plasse
Isaac
Olivia Wilde
Princess Inanna
Paul Scheer
Bricklayer
Jack Black
Zed
David Pasquesi
Prime Minister
June Diane Raphael
Maya
Gene Stupnitsky
First Guard
Lee Eisenberg
Sodom Sentry
Matthew Willig
Marlak
Gabriel Sunday
Seth
Marshall Manesh
Slave Trader
Matt Besser
Guy in Crowd
Sarah Christine Smith
Dancer
Eden Riegel
Lilith
Bryan Massey
New Guard
Kelly Connolly
Dancer
Leslie Geldbach
Dancer