Elsa Lanchester
Elsa (Mrs Charles) Smith
George Sanders
Williams
Thomas Mitchell
John Halloway
Marcel Dalio
Second Salesman at Sandelli's (uncredited)
Cesar Romero
Harry Wilson
Henry Fonda
George
Eugene Pallette
Luther - Orman's butler
Mae Marsh
Molly (Robinson sequence)
Margaret Dumont
Mme. Langehanke (uncredited)
Charles Laughton
Charles Smith
Harry Davenport
Prof. Lyons
Edward G. Robinson
Avery L. 'Larry' Browne
W.C. Fields
Professor Pufflewhistle
Roland Young
Edgar - Wilson's butler
Charles Boyer
Paul Orman
Victor Francen
Arturo Bellini - Symphony conductor
Ginger Rogers
Diane
Frank Orth
Secondhand Clothes Dealer (Rogers sequence)
James Gleason
Joe - Mission Aid Society
J. Carrol Naish
Burglar - Robber #1
Rita Hayworth
Ethel Halloway
Will Wright
Old Concertgoer (Laughton sequence) (uncredited)
Phil Silvers
First Salesman at Santelli's (uncredited)
Morris Ankrum
Judge
Morris Ankrum
Judge Tom Barnes (Robinson sequence)
Marion Martin
'Squirrel' Grey
Clarence Muse
Grandpa (Robeson sequence)
Donald Douglas
'Hen 'Henderson (Robinson sequence) (as Don Douglas)
Paul Robeson
Luke
Ethel Waters
Esther
Eddie 'Rochester' Anderson
Rev. Lazarus
Gail Patrick
Ellen - Diane's friend
Harry Hayden
'Soupy' Davis (Robinson sequence)
Adeline De Walt Reynolds
Elsa's Old Mother (Laughton sequence)
Helene Reynolds
Actress (Boyer sequence)
Cordell Hickman
Little Nicodemus (Robeson sequence)
James Rennie
H.R. 'Hank' Bronson (Robinson sequence)
Blue Washington
Shantytown Man (Robeson sequence) (uncredited)
Rondo Hatton
Party Guest (uncredited)
Christian Rub
Cello Player (Laughton sequence)