Dwight Frye
Wilmer Cook
J. Farrell MacDonald
Det. Sgt. Tom Polhaus
Una Merkel
Effie Perrine
Bebe Daniels
Ruth Wonderly
Ricardo Cortez
Sam Spade
Thelma Todd
Iva Archer
Morgan Wallace
District Attorney (uncredited)
Dudley Digges
Casper Gutman
Otto Matieson
Dr. Joel Cairo
Walter Long
Miles Archer
Robert Elliott
Police Lt. Dundy
Agostino Borgato
Capt. John Jacobi (uncredited)
Lucille Ward
Sarah the Prison Matron (uncredited)