Nicolas Cage
Peter Parker / Spider-Man Noir (voice)
Stan Lee
Stan (voice)
Lily Tomlin
Aunt May (voice)
Rif Hutton
Additional Voices (voice)
Kathryn Hahn
Olivia 'Liv' Octavius / Doc Ock (voice)
Claudia Choi
Brooklyn Visions Teacher (voice)
Liev Schreiber
Wilson Fisk / Kingpin (voice)
Oscar Isaac
Interesting Person #1 (voice)
Lake Bell
Vanessa Fisk (voice)
Zoƫ Kravitz
Mary Jane (voice)
Caitlin McKenna
Additional Voices (voice)
Terrence Hardy Jr.
Additional Voices (voice)
Chris Pine
Peter Parker / Spider-Man (voice)
Jorma Taccone
Green Goblin / Last Dude (voice)
Courtney Peldon
Additional Voices (voice)
JoaquĆn CosĆo
Scorpion (voice)
Chrystee Pharris
Additional Voices (voice)
Scott Menville
Additional Voices (voice)
Natalie Morales
Miss Calleros (voice)
Hailee Steinfeld
Gwen Stacy / Spider-Woman (voice)
Luna Lauren Velez
Rio Morales (voice)
Jacqueline Pinol
Additional Voices (voice)
Christopher Miller
Additional Voices (voice)
Nick Jaine
Brooklyn Visions Teacher (voice)
Justin Shenkarow
Additional Voices (voice)
June Christopher
Additional Voices (voice)
Bridget Hoffman
Additional Voices (voice)
Darcy Rose Byrnes
Additional Voices (voice)
Brian Tyree Henry
Jefferson Davis (voice)
Jake Johnson
Peter B. Parker / Spider-Man (voice)
Lex Lang
Additional Voices (voice)
Devika Parikh
Additional Voices (voice)
Shameik Moore
Miles Morales / Spider-Man (voice)
Melissa Sturm
Additional Voices (voice)
Carlos Zaragoza
Brooklyn Visions Teacher (voice)
Mahershala Ali
Uncle Aaron / Prowler (voice)
John Mulaney
Peter Porker / Spider-Ham (voice)
Harrison Knight
Additional Voices (voice)
Oscar Camacho
Additional Voices (voice)
Holly Walker
Additional Voices (voice)
Al Rodrigo
Additional Voices (voice)
Kim Yarbrough
Scientist in Cafeteria (voice)
Greta Lee
Interesting Person #2 (voice)
Juan Pacheco
Additional Voices (voice)
Jon Bruno
Additional Voices (voice)
Kimiko Glenn
Peni Parker (voice)
Ruth Zalduondo
Additional Voices (voice)
Joseph Izzo
Brooklyn Visions Teacher (voice)
Melanie Haynes
Brooklyn Visions Teacher (voice)
Juan Carlos Arvelo
Additional Voices (voice)
Miguel Jiron
Additional Voices (voice)
Donna Lynn Leavy
Additional Voices (voice)
Jessica Mikayla Adams
Brooklyn Friend (voice)
Michelle Jubilee Gonzalez
Additional Voices (voice)
Juan Pope
Additional Voices (voice)
Edwin H. Bravo
Brooklyn Visions Security Guard (voice)
Mimi Davila
Brooklyn Visions Student (voice)
Post Malone
Brooklyn Bystander (voice)
Marvin 'Krondon' Jones III
Tombstone (voice)
Arthur Ortiz
Additional Voices (voice)
Muneeb Rehman
Brooklyn Visions Teacher (voice)
Warren Sroka
Additional Voices (voice)
Shakira Ja'nai Paye
Additional Voices (voice)
Dennis Singletary
Additional Voices (voice)
Joseph Sanfelippo
Additional Voices (voice)
Alycia Cooper
Additional Voices (voice)
Sarah D. Cole
Brooklyn Friend (voice)
Jason Linere-White
Additional Voices (voice)