Lionel Atwill
Dr. Suderman
Leo G. Carroll
Professor Gordon
Cora Witherspoon
Susie Watson
James Burke
Wilkie, house detective
Charles Middleton
Jeremiah Walters
Paul McVey
Mrs. Pendleton's Doctor
Don Beddoe
Frederick Ross
C. Montague Shaw
Inspector Duff
Emmett Vogan
Hotel Manager
Robert Lowery
Dick Kenyon
Harlan Briggs
San Francisco Coroner
Marjorie Weaver
Paula Drake
Sidney Toler
Charlie Chan
Kay Linaker
Linda Pendleton
Claire Du Brey
Sarah Walters
Victor Sen Yung
Jimmy Chan
Cliff Clark
Lieutenant Wilson
Walter Miller
Ship's Officer (uncredited)
Leonard Mudie
Gerald Pendleton
Richard Keene
Buttons, ship's steward
Al Kikume
Cop Extra in Chan's Office
Layne Tom Jr.
Willie Chan
Wade Boteler
Honolulu Police Chief
Harry Strang
Seaman Guarding Pendleton
John Dilson
Police Doctor at Hotel
J. Anthony Hughes
Detective Wilson, Chan's agent