Philip Seymour Hoffman
Caden Cotard
Emily Watson
Tammy
Michelle Williams
Claire Keen
Dianne Wiest
Ellen Bascomb / Millicent Weems
Samantha Morton
Hazel
Catherine Keener
Adele Lack
Michael Higgins
Actor Playing Man with Nose Bleed
Josh Pais
Ophthalmologist
Gerald Emerick
Man in Line
Rosemary Murphy
Frances
Lynn Cohen
Caden's Mother
Jennifer Jason Leigh
Maria
Hope Davis
Madeleine Gravis
Sadie Goldstein
Olive (4 years old)
Alice Drummond
Actress Playing Frances
Jerry Adler
Caden's Father
Tim Guinee
Needleman Actor
Frank Wood
Evaluative Services Doctor
Peter Friedman
Emergency Room Doctor
Christopher Evan Welch
Pastor
John Rothman
Dentist
Portia
Therapy Patient Actress
Dan Ziskie
Leg Tremor Doctor
Deirdre O'Connell
Ellen's Mother
Robin Weigert
Adult Olive
Daisy Tahan
Ariel
Amy Wright
Burning House Realtor
Nicholas Wyman
Soap Actor Doctor
Daniel London
Tom
Stephen Adly Guirgis
Davis
Tom Noonan
Sammy Barnathan
Elizabeth Marvel
Warehouse Realtor
Charles Techman
Like Clockwork Patient
Frank Girardeau
Plumber
Michael Medeiros
Eric
Paul Sparks
Derek
Alvin Epstein
Man with Nose Bleed
Kristen Bush
Actress Playing Claire
Robert Seay
David
Joe Lisi
Maurice
Amy Spanger
Soap Actress Nurse
Mark Lotito
Minister
Tom Greer
Medic
Barbara Haas
Warehouse Actress
Chris McGinn
Lady at Caden's Mom's
Erica Fae
German Woman
William Ryall
Jimmy