Antonio Banderas
Gregorio Cortez (uncredited)
Angela Lanza
Female OSS Agent
Danny Trejo
Uncle Machete
Jeremy Piven
Danger D'Amo / Tick Tock / Time Keeper
Ricky Gervais
Voice of Argonaut
Jonathan Breck
Wilbur's Boss
Jessica Alba
Marissa Wilson
Alexa PenaVega
Carmen Cortez
Daryl Sabara
Juni Cortez
Joel McHale
Wilbur Wilson
Wray Crawford
Editor / Cameraman
Chad Guerrero
Henchman in Van
Mason Cook
Cecil Wilson
Roger Edwards
OSS Agent #2
Rowan Blanchard
Rebecca Wilson